NCIt related terms : Leo 299; Estramustine phosphate; Estracyt; Estramustine sodium phosphate;
NCIt definition : The orally available disodium salt, monohydrate, of estramustine phosphate, a synthetic
molecule that combines estradiol and nornitrogen mustard through a carbamate link.
Estramustine and its major metabolite estramustine bind to microtubule-associated
proteins (MAPs) and tubulin, thereby inhibiting microtubule dynamics and leading to
anaphase arrest in a dose-dependent fashion. This agent also exhibits anti-androgenic
effects.;
UNII : 75F375MT2N;
InChIKey : OAIHMBRTKDWZQG-WFVUJJAZSA-L;
CAS number : 52205-73-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 52205-73-9
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