" /> Diclofenac Sodium - CISMeF





Preferred Label : Diclofenac Sodium;

NCIt synonyms : 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Monosodium Salt;

NCIt related terms : Voltaren;

NCIt definition : The sodium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity. Diclofenac sodium is a non-selective reversible and competitive inhibitor of cyclooxygenase (COX), subsequently blocking the conversion of arachidonic acid into prostaglandin precursors. This leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever.;

Alternative definition : NCI-GLOSS: A drug that is used to treat the symptoms of rheumatoid arthritis and is being studied in the prevention and treatment of some types of skin cancer. It blocks substances that cause inflammation and pain. It may also prevent the growth of new blood vessels that tumors need to grow. It is a type of cyclooxygenase inhibitor, a type of nonsteroidal anti-inflammatory drug (NSAID), and a type of antiangiogenesis agent.;

UNII : QTG126297Q;

InChIKey : KPHWPUGNDIVLNH-UHFFFAOYSA-M;

CAS number : 15307-79-6;

Drug name : Voltaren;

Molecule name : GP 45840;

Chemical formula : C14H10Cl2NO2.Na;

ChEBI ID : CHEBI:4509;

Codes from synonyms : CDR0000617661; CDR0000617660; 09109;

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07/05/2025


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