Preferred Label : Demeclocycline;
NCIt synonyms : 7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide;
NCIt definition : A semi-synthetic, broad-spectrum naphthacene antibiotic produced by the bacterium
Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S ribosomal subunit
and prevents binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting
protein synthesis. Demeclocycline also inhibits the effect of vasopressin on the renal
tubules, thereby causing diuresis.;
UNII : 5R5W9ICI6O;
InChIKey : FMTDIUIBLCQGJB-SEYHBJAFSA-N;
CAS number : 127-33-3;
Chemical formula : C21H21ClN2O8;
ChEBI ID : CHEBI:4392;
Origin ID : C47980;
UMLS CUI : C0011276;
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
concept_is_in_subset
has_salt_form
is_free_acid_or_base_form_of