" /> Clonidine Hydrochloride - CISMeF





Preferred Label : Clonidine Hydrochloride;

NCIt related terms : Catapres;

NCIt definition : The hydrochloride salt form of clonidine, an imidazoline derivate and centrally-acting alpha-adrenergic agonist as well as antagonist with antihypertensive activity. Clonidine hydrochloride binds to and stimulates central alpha-2 adrenergic receptors, thereby decreasing sympathetic outflow to the heart, kidneys, and peripheral vasculature. The reduction in sympathetic outflow, leads to decreased peripheral vascular resistance, decreased blood pressure, and decreased heart rate.;

Alternative definition : NCI-GLOSS: A drug used to treat high blood pressure. It is also being studied in the treatment of certain types of cancer pain. It blocks the release of chemicals from nerve endings that make blood vessels constrict (get narrower). Catapres is a type of antihypertensive agent and a type of alpha-adrenergic agonist.;

UNII : W76I6XXF06;

InChIKey : ZNIFSRGNXRYGHF-UHFFFAOYSA-N;

CAS number : 4205-91-8;

Drug name : Catapres;

Chemical formula : C9H9Cl2N3.HCl;

Codes from synonyms : CDR0000630974; 32051; CDR0000630975;

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19/06/2025


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