Acyclovir Sodium

Preferred Label : Acyclovir Sodium;

NCIt synonyms : 9-((2-Hydroxyethoxy)methyl)guanine Monosodium Salt; 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one Momsodium Salt;

NCIt definition : The sodium salt form of acyclovir, a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family. After conversion in vivo to the active metabolite acyclovir triphosphate by viral thymidine kinase, acyclovir competitively inhibits viral DNA polymerase by incorporating into the growing viral DNA chain and terminating further polymerization.;

UNII : 927L42J563;

InChIKey : RMLUKZWYIKEASN-UHFFFAOYSA-M;

CAS number : 69657-51-8;

Drug name : Zovirax for Injection;

Chemical formula : C8H10N5O3.Na;

Details

Origin ID

C47956;

UMLS CUI

C0282040;

Automatic exact mappings (from CISMeF team)
- acyclovir [MeSH Descriptor]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Aciclovir sodium (substance) [SNOMED CT concept]
- Acyclovir Sodium [MeSH concept]
- acyclovir sodium [SNOMED Notion]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Acyclovir [NCIt concept]
is_salt_form_of
- Acyclovir [NCIt concept]

Keyword's position in hierarchy(ies) :

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