Acyclovir - CISMeF

Preferred Label : Acyclovir;

NCIt synonyms : ACV; Acycloguanosine; 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one; 9-[(2-Hydroxyethoxy)methyl]guanine; Aciclovir;

NCIt related terms : 9-[(2-Hydroxyethoxy)-methyl]guanine;

NCIt definition : A synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family. After conversion in vivo to the active metabolite acyclovir triphosphate by viral thymidine kinase, acyclovir competitively inhibits viral DNA polymerase by incorporating into the growing viral DNA chain and terminating further polymerization.;

Alternative definition : NCI-GLOSS: A substance used to prevent or treat cytomegalovirus and herpes simplex infections that may occur when the body is immunosuppressed. It belongs to the family of drugs called antivirals.;

UNII : X4HES1O11F;

InChIKey : MKUXAQIIEYXACX-UHFFFAOYSA-N;

CAS number : 59277-89-3;

Drug name : Acicloftal; Virorax; Zovirax; Aclovir; Cargosil;

Molecule name : BW-248U; Wellcome-248U;

Chemical formula : C8H11N5O3;

NCI Metathesaurus CUI : CL523878;

NSC code : 335752; 645011;

ChEBI ID : CHEBI:2453;

Codes from synonyms : CDR0000045167; NSC0645011; 11;

Details

Origin ID

C205;

UMLS CUI

C0001367;

Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Aciclovir [ICD-11 Extension code]
- Aciclovir (substance) [SNOMED CT concept]
- Acyclovir [LOINC component]
- Ophthalmic form acyclovir (product) [Inactive SNOMED CT concept]
- Product containing aciclovir (medicinal product) [SNOMED CT concept]
- aciclovir [ATC Code]
- aciclovir [ATC Code]
- aciclovir [ATC Code]
- acyclovir [Substance BNPC]
- acyclovir [MeSH Descriptor]
- acyclovir [MeSH concept]
- acyclovir [SNOMED Notion]
Validated automatic mappings to BTNT
- aciclovir [ATC Code]
- aciclovir [ATC Code]
- aciclovir [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Acyclovir Sodium [NCIt concept]
is_component_of_chemotherapy_regimen
- Acyclovir/Zidovudine [NCIt concept]
is_free_acid_or_base_form_of
- Acyclovir Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients