" /> Pramocaine Hydrochloride - CISMeF





Preferred Label : Pramocaine Hydrochloride;

NCIt synonyms : Tronothane; 4-(3-(p-Butoxyphenoxy)propyl)morpholine Hydrochloride;

NCIt related terms : PRAMOXINE HYDROCHLORIDE;

NCIt definition : The hydrochloride salt form of pramoxine, a morpholine derivative with local anesthetic property. Pramocaine hydrochloride decreases the permeability of the neuronal membrane to sodium ions by reversibly binding to and inhibiting voltage-gated sodium channels. This results in stabilization of the membrane and, thereby inhibiting the ionic fluxes required for membrane depolarization, hence resulting in the failure to initiate a propagated action potential and subsequent conduction blockade.;

UNII : 88AYB867L5;

InChIKey : SYCBXBCPLUFJID-UHFFFAOYSA-N;

CAS number : 637-58-1;

Drug name : Tronolane; Fleet;

Chemical formula : C17H27NO3.HCl;

NSC code : 25573;

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10/05/2025


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