NCIt definition : The citrate salt of piperazine, a cyclic amine with anthelminthic property. Piperazine
citrate is a gamma-aminobutyric acid GABA receptor agonist and blocks the activity
of acetylcholine at the neuromuscular junction thereby altering neuronal cell membrane
permeability and causing hyperpolarization. This results in flaccid paralysis of worm
musculature allowing the worm to become dislodged by peristalsis and expelled from
the body.;