Preferred Label : Molindone Hydrochloride;
NCIt synonyms : Lidone; 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, Monohydrochloride;
NCIt definition : The hydrochloride salt form of molindone, a dihydroindolone compound with antipsychotic
and anti-schizophrenic properties not structurally related to other major tranquilizers.
Molindone hydrochloride exerts its effect by blocking dopamine receptors, probably
D2 and D3, in the reticular activating and limbic systems, thereby decreasing dopamine
excess in the brain. This leads to a reduction of spontaneous locomotion and aggressiveness,
suppression of conditioned response, antagonism of stereotyped behaviour and hyperactivity
induced by amphetamines.;
UNII : 1DWS68PNE6;
InChIKey : GQWNECFJGBQMBO-UHFFFAOYSA-N;
CAS number : 15622-65-8;
Drug name : Moban;
Chemical formula : C16H24N2O2.HCl;
Origin ID : C47624;
UMLS CUI : C0282249;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
