Preferred Label : molindone;
MeSH definition : An indole derivative effective in schizophrenia and other psychoses and possibly useful
in the treatment of the aggressive type of undersocialized conduct disorder. Molindone
has much lower affinity for D2 receptors than most antipsychotic agents and has a
relatively low affinity for D1 receptors. It has only low to moderate affinity for
cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals
indicate that molindone has certain characteristics that resemble those of CLOZAPINE.
(From AMA Drug Evaluations Annual, 1994, p283);
CISMeF synonym : 15622-65-8 (Molindone hydrochloride); endo brand of molindone hydrochloride;
MeSH hyponym : moban; Molindone Hydrochloride; Hydrochloride, Molindone; Molindone Monohydrochloride; Monohydrochloride, Molindone;
MeSH CAS label : 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-;
MeSH Related Number : molindone hydrochloride; 15622-65-8 (mono-HCl); 7416-34-4 (Molindone); 1DWS68PNE6;
Registry Number MeSH : 7416-34-4;
Related CAS MeSH : 1DWS68PNE6 (Molindone hydrochloride);
Wikipedia link : https://en.wikipedia.org/wiki/Molindone;
Is substance : O;
UNII : RT3Y3QMF8N;
InChIKey : KLPWJLBORRMFGK-UHFFFAOYSA-N;
Origin ID : D008972;
UMLS CUI : C0026388;
ATC code(s)
- Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Pharmacological action(s)
- Record concept(s)
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
An indole derivative effective in schizophrenia and other psychoses and possibly useful
in the treatment of the aggressive type of undersocialized conduct disorder. Molindone
has much lower affinity for D2 receptors than most antipsychotic agents and has a
relatively low affinity for D1 receptors. It has only low to moderate affinity for
cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals
indicate that molindone has certain characteristics that resemble those of CLOZAPINE.
(From AMA Drug Evaluations Annual, 1994, p283)
