Guanfacine Hydrochloride

Preferred Label : Guanfacine Hydrochloride;

NCIt synonyms : Estulic; N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide Hydrochloride;

NCIt definition : The hydrochloride salt form of guanfacine, a centrally acting alpha-2 adrenergic agonist with antihypertensive activity. Alpha-2 receptor stimulation by guanfacine hydrochloride results in a decreased sympathetic outflow from the vasomotor center to the heart, kidneys, and peripheral vasculature. This leads to a decrease in heart rate and peripheral vascular resistance. (NCI05);

UNII : PML56A160O;

InChIKey : DGFYECXYGUIODH-UHFFFAOYSA-N;

CAS number : 29110-48-3;

Drug name : Tenex;

Chemical formula : C9H9Cl2N3O.HCl;

Details

Origin ID

C47550;

UMLS CUI

C0700472;

See also inter- (CISMeF)
- Guanfacine hydrochloride (product) [Inactive SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Guanfacine hydrochloride (product) [Inactive SNOMED CT concept]
- Guanfacine hydrochloride (substance) [SNOMED CT concept]
- N-(Aminoiminomethyl)-2,6-dichlorophenylacetamide monohydrochloride [Substance BNPC]
- guanfacine hydrochloride [MeSH concept]
Validated automatic mappings to BTNT
- estulic [MeSH concept]
Validated automatic mappings to NTBT
- guanfacine [Substance BNPC]
- guanfacine [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Guanfacine [NCIt concept]
is_salt_form_of
- Guanfacine [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients