" /> Galantamine Hydrobromide - CISMeF





Preferred Label : Galantamine Hydrobromide;

NCIt synonyms : Lycoremine Hydrobromide; Nivalin; Benzofuro(4,3,2-efg)(2)benzazocin-6-ol, 1,2,3,4,6,7,7a,11c-octahydro-9-methoxy-2-methyl-, Hydrobromide; Reminyl;

NCIt definition : The hydrobromide salt form of galantamine, a tertiary alkaloid obtained synthetically or naturally from the bulbs and flowers of Narcissus and several other genera of the Amaryllidaceae family with anticholinesterase and neurocognitive-enhancing activities. Galantamine competitively and reversibly inhibits acetylcholinesterase, thereby increasing the concentration and enhancing the action of acetylcholine (Ach). In addition, galantamine is a ligand for nicotinic acetylcholine receptors, which may increase the presynaptic release of Ach and activate postsynaptic receptors. This agent may improve neurocognitive function in mild and moderate Alzheimer' s disease and may reduce abstinence-induced cognitive symptoms that promote smoking relapse.;

UNII : MJ4PTD2VVW;

InChIKey : QORVDGQLPPAFRS-XPSHAMGMSA-N;

CAS number : 69353-21-5; 1953-04-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 69353-21-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1953-04-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Razadyne;

Chemical formula : C17H21NO3.BrH;

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15/05/2024


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