Preferred Label : Galantamine Hydrobromide;
NCIt synonyms : Lycoremine Hydrobromide; Nivalin; Benzofuro(4,3,2-efg)(2)benzazocin-6-ol, 1,2,3,4,6,7,7a,11c-octahydro-9-methoxy-2-methyl-,
Hydrobromide; Reminyl;
NCIt definition : The hydrobromide salt form of galantamine, a tertiary alkaloid obtained synthetically
or naturally from the bulbs and flowers of Narcissus and several other genera of the
Amaryllidaceae family with anticholinesterase and neurocognitive-enhancing activities.
Galantamine competitively and reversibly inhibits acetylcholinesterase, thereby increasing
the concentration and enhancing the action of acetylcholine (Ach). In addition, galantamine
is a ligand for nicotinic acetylcholine receptors, which may increase the presynaptic
release of Ach and activate postsynaptic receptors. This agent may improve neurocognitive
function in mild and moderate Alzheimer' s disease and may reduce abstinence-induced
cognitive symptoms that promote smoking relapse.;
UNII : MJ4PTD2VVW;
InChIKey : QORVDGQLPPAFRS-XPSHAMGMSA-N;
CAS number : 69353-21-5; 1953-04-4;
Drug name : Razadyne;
Chemical formula : C17H21NO3.BrH;
Origin ID : C47546;
UMLS CUI : C0949312;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- has_free_acid_or_base_form
- has_target
- is_salt_form_of
