NCIt definition : The fumarate salt form of formoterol, a long-acting and selective sympathomimetic
beta-receptor agonist with bronchodilator activity. Formoterol fumarate binds beta
2 adrenergic receptors in bronchial smooth muscle and stimulates intracellular adenyl
cyclase, thereby increasing the production of cyclic adenosine monophosphate (cAMP).
Increased cAMP levels cause relaxation of bronchial smooth muscle, improve mucociliary
clearance and reduce mediator substance release in inflammatory cells, especially
from mast cells. (NCI05);