NCIt definition : A phenothiazine with antipsychotic activity. Fluphenazine exerts its actions by blocking
postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia.
This prevents the actions of dopamine, thereby reducing the hallucinations and delusions
that are associated with schizophrenia.;
Alternative definition : NCI-GLOSS: A drug that is used to treat mental and emotional disorders and is being
studied in the treatment of multiple myeloma. Fluphenazine may stop tumor growth by
keeping myeloma cells from dividing and causing them to die. It is a type of antipsychotic.;