Estazolam - CISMeF

Preferred Label : Estazolam;

NCIt synonyms : Esilgan; 8-Chloro-6-phenyl-4H-(1,2,4)triazolo-(4,3-a)(1,4)benzodiazepine;

NCIt definition : A triazolo-benzodiazepine with anxiolytic, anticonvulsant, hypnotic, and muscle relaxant properties. Estazolam binds to the gamma-aminobutyric acid (GABA) receptor at a site distinct from the inhibitory neurotransmitter GABA binding site in the limbic system of the central nervous system (CNS). This binding leads to an opening of the chloride channels, which allows the flow of chloride ions into the neuron, hyperpolarizes the neuronal membrane, inhibits neuronal firing, and leads to a decrease in neuronal excitability.;

UNII : 36S3EQV54C;

InChIKey : CDCHDCWJMGXXRH-UHFFFAOYSA-N;

CAS number : 29975-16-4;

Drug name : ProSom;

Chemical formula : C16H11ClN4;

NSC code : 290818;

ChEBI ID : CHEBI:4858;

Details

Origin ID

C47520;

UMLS CUI

C0014892;

Automatic exact mappings (from CISMeF team)
- proteasome endopeptidase complex [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Estazolam [ICD-11 Extension code]
- Estazolam [LOINC component]
- Estazolam (substance) [SNOMED CT concept]
- Product containing estazolam (medicinal product) [SNOMED CT concept]
- estazolam [ATC Code]
- estazolam [Substance BNPC]
- estazolam [MeSH concept]
- estazolam [MeSH Descriptor]
- estazolam [SNOMED Notion]
Validated automatic mappings to BTNT
- estazolam [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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