Preferred Label : Doxylamine Succinate;
NCIt synonyms : Mereprine; Sedaplus; Unisom; Butanedioic Acid, compound with N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine(1:1); Dimethylaminoethoxy-methyl-benzyl-pyridine Succinate; Decapryn; N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy] ethanamine, butanedioate(1:1);
NCIt definition : A pyridine derivate histamine H1 antagonist with pronounced sedative properties. Doxylamine
succinate competitively blocks the histamine H1 receptor and limits the typical allergic
and anaphylactic responses, including bronchoconstriction, vasodilation, increased
capillary permeability, and spasmodic contraction of gastrointestinal smooth muscle,
caused by actions of histamine on bronchial and gastrointestinal smooth muscles, and
on capillaries. This drug also prevents histamine-induced pain and itching of the
skin and mucous membranes.;
UNII : V9BI9B5YI2;
InChIKey : KBAUFVUYFNWQFM-UHFFFAOYSA-N;
CAS number : 562-10-7;
Chemical formula : C17H22N2O.C4H6O4;
NSC code : 74772;
Origin ID : C47501;
UMLS CUI : C0058733;
Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
