NCIt definition : The sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase
resistant, second-generation cephalosporin antibiotic with bactericidal activity.
Cefuroxime sodium inhibits bacterial cell wall synthesis by inactivating penicillin
binding proteins (PBPs) thereby interfering with the final transpeptidation step required
for cross-linking of peptidoglycan units which are a component of the cell wall. Lack
of cross-linking results in a reduction of cell wall stability and leads to cell lysis.;
Semantic type(s)