Splenic Marginal Zone Lymphoma

Preferred Label : Splenic Marginal Zone Lymphoma;

NCIt synonyms : Splenic Marginal Zone Lymphoma with Villous Lymphocytes; Splenic Marginal Zone B-Cell Lymphoma with Villous Lymphocytes; Marginal Zone Lymphoma of the Spleen; Marginal Zone Lymphoma of Spleen; Splenic Lymphoma with Circulating Villous Lymphocytes; SLVL; SMZL;

NCIt related terms : Splenic marginal zone lymphoma, NOS; Splenic marginal zone B-cell lymphoma;

CISMeF acronym : SMZL; SLVL;

NCIt definition : A B-cell non-Hodgkin lymphoma composed of small lymphocytes which surround and replace the splenic white pulp germinal centers. It involves the spleen and splenic hilar lymph nodes, bone marrow, and often the peripheral blood. When lymphoma cells are present in the peripheral blood, they are usually, but not always, characterized by the presence of short polar villi. (WHO);

Neoplastic status : Malignant;

ICD-O code : 9689/3;

Détails

Origin ID

C4663;

UMLS CUI

C0349632;

Automatic exact mappings (from CISMeF team)
- Marginal zone lymphoma, spleen [ICD-9 code]
- Small cell B-cell lymphoma [ICD-10 Sub-category]
- Splenic marginal zone B-cell lymphoma [ICD-11 More detail]
- Splenic marginal zone B-cell lymphoma (disorder) [SNOMED CT concept]
- Splenic marginal zone lymphoma [ICD-11 More detail]
Currated CISMeF NLP mapping
- Marginal zone lymphoma of spleen (disorder) [SNOMED CT concept]
- Splenic marginal zone B-cell lymphoma [ICD-O code]
- Splenic marginal zone B-cell lymphoma (morphologic abnormality) [SNOMED CT concept]
- Splenic marginal zone lymphoma [MedDRA Preferred Term]
- Splenic marginal zone lymphoma [ORDO Disease]
- Splenic marginal zone lymphoma NOS [MedDRA LLT]
- Splenic marginal zone lymphomas [MedDRA High Level Term]
- splenic marginal zone B cell lymphoma [Disease (Nov.)]
- splenic marginal zone lymphoma [DO Concept]
Disease excludes abnormal cell
- Lymphocyte Predominant Cell [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- Monoclonal Gammopathy [NCIt concept]
- Peripheral Blood Involvement [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
- Spleen [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Marginal zone lymphoma of spleen (disorder) [SNOMED CT concept]
- Marginal zone lymphoma, spleen [ICD-9 code]
- Splenic lymphoma with villous lymphocytes (disorder) [SNOMED CT concept]
- Splenic marginal zone B-cell lymphoma [ICD-O code]
- Splenic marginal zone B-cell lymphoma (disorder) [SNOMED CT concept]
- Splenic marginal zone B-cell lymphoma (morphologic abnormality) [SNOMED CT concept]
- Splenic marginal zone lymphoma [ORDO Disease]
- Splenic marginal zone lymphoma [MedDRA Preferred Term]
- Splenic marginal zone lymphoma NOS [MedDRA LLT]
- Splenic marginal zone lymphomas [MedDRA High Level Term]
- splenic marginal zone B cell lymphoma [Disease (Nov.)]
- splenic marginal zone lymphoma [DO Concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Aggressive Clinical Course [NCIt concept]
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic Small to Medium-Sized B-Lymphocyte with Pale Cytoplasm [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
- Splenomegaly [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Marginal Zone B-Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
- Postgerminal Center B-Lymphocyte of Unknown Differentiation Stage [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
- Marginal Zone [NCIt concept]
- Splenic Marginal Zone [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
- Spleen [NCIt concept]
disease_may_have_abnormal_cell
- Neoplastic Plasma Cell [NCIt concept]
- Villous Lymphocyte [NCIt concept]
disease_may_have_associated_disease
- Anemia [NCIt concept]
- Hepatitis C Infection [NCIt concept]
- Thrombocytopenia Due to Immune Destruction [NCIt concept]
disease_may_have_cytogenetic_abnormality
- del(7q21-q32) [NCIt concept]
disease_may_have_molecular_abnormality
- KLF2 Gene Mutation [NCIt concept]
- KMT2D Gene Mutation [NCIt concept]
- NOTCH2 Gene Mutation [NCIt concept]
- TNFAIP3 Gene Mutation [NCIt concept]
- TP53 Gene Mutation [NCIt concept]

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