NCIt definition : A synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity.
Doxycycline binds to the 30S ribosomal subunit, possibly to the 50S ribosomal subunit
as well, thereby blocking the binding of aminoacyl-tRNA to the mRNA-ribosome complex.
This leads to an inhibition of protein synthesis. In addition, this agent has exhibited
inhibition of collagenase activity.;
Alternative definition : NCI-GLOSS: A drug used to treat many types of bacterial infections. It stops the growth
of bacteria by keeping them from making proteins. It is a type of antibiotic.;