NCIt definition : The hyclate salt form of doxycycline, a synthetic, broad-spectrum tetracycline antibiotic
exhibiting antimicrobial activity. Doxycycline hyclate binds reversibly to the 30S
ribosomal subunit, possibly to the 50S ribosomal subunit as well, thereby blocking
the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This leads to an inhibition
of protein synthesis. In addition, this agent has exhibited inhibition of collagenase
activity.;
Alternative definition : NCI-GLOSS: A drug used to treat many types of bacterial infections. It stops the growth
of bacteria by keeping them from making proteins. It is a type of antibiotic.;