" /> CYP2C9*1 Allele - CISMeF





Preferred Label : CYP2C9*1 Allele;

NCIt synonyms : CYP2C9, Wild-Type; Cytochrome P450, Family 2, Subfamily C, Polypeptide 9*1 Allele; CYP2C9, g.-2665delTG, g.-1188T C; CYP2C9*1; CYP2C9 1 Allele;

NCIt definition : Human CYP2C9*1 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9 wild-type allele, encodes cytochrome P450 2C9*1 protein. There are multiple haplotypes of this allele. The nucleotide sequence of CYP2C9*1A is identical to that of the wild-type allele and exhibits no mutations. Three other haplotypes of this allele exhibit a deletion (g.-2665delTG) and/or a SNP (g.-1188T C) in the 5'- flanking region upstream of the gene. However, these nucleotide changes have no effect on the enzymatic activity of the corresponding cytochrome P450 2C9*1 protein.;

GenBank Accession Number : NM_000771;

PubMed : 15608560;

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20/05/2024


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