Dopamine Hydrochloride

Preferred Label : Dopamine Hydrochloride;

NCIt synonyms : Dopaminergic; Dopamine;

NCIt definition : The hydrochloride salt form of dopamine, a monoamine compound with positive inotropic activity. Dopamine is a naturally occurring catecholamine formed by decarboxylation of dehydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine binds to alpha-1- and beta-1- adrenergic receptors. Mediated through myocardial beta-1-adrenergic receptors, dopamine increase heart rate and force, thereby increasing cardiac output. Alpha-1-adrenergic receptor stimulation on vascular smooth muscle, leads to vasoconstriction and results in an increase in systemic vascular resistance. Stimulation of dopaminergic receptors in renal vasculature, leads to renal blood vessel dilation, and an increase in glomerular filtration rate, renal blood flow, sodium excretion, and urine output.;

UNII : 7L3E358N9L;

InChIKey : CTENFNNZBMHDDG-UHFFFAOYSA-N;

CAS number : 62-31-7;

Chemical formula : C8H11NO2.HCl;

NSC code : 173182;

Details

Origin ID

C455;

UMLS CUI

C0282151;

Automatic exact mappings (from CISMeF team)
- Dopamine [FMA entity]
- Dopamine [ICHI extension code]
- Product containing dopamine (medicinal product) [SNOMED CT concept]
- dopamine [MeSH Descriptor]
- dopamine [Substance BNPC]
- dopamine [ATC Code]
- dopamine [EMDN type]
- dopamine [medical devices type]
- dopamine [Artificial nutrition thesaurus concept]
- dopamine agents [MeSH Descriptor]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- DOPamine [LOINC component]
- Dopamine [FMA entity]
- Dopamine [ICD-11 Extension code]
- Dopamine [SMS substance]
- Dopamine (substance) [SNOMED CT concept]
- dopamine [MeSH Descriptor]
- dopamine [Substance BNPC]
- dopamine [MeSH concept]
- dopamine [SNOMED Notion]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Dopamine [NCIt concept]
is_salt_form_of
- Dopamine [NCIt concept]

Keyword's position in hierarchy(ies) :

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