Zalcitabine - CISMeF

Preferred Label : Zalcitabine;

NCIt synonyms : Dideoxycytidine; 2',3'-Dideoxycytidine; ddC;

NCIt definition : A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zalcitabine preferentially inhibits the gamma form of DNA polymerase present in tumor cell mitochondria, resulting in the inhibition of tumor cell mitochondrial DNA replication and tumor cell death. (NCI04);

UNII : 6L3XT8CB3I;

InChIKey : WREGKURFCTUGRC-POYBYMJQSA-N;

CAS number : 7481-89-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 7481-89-2 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Hivid;

Chemical formula : C9H13N3O3;

NSC code : 606170;

ChEBI ID : CHEBI:10101;

Codes from synonyms : NSC0606170;

Details

Origin ID

C430;

UMLS CUI

C0012132;

Currated CISMeF NLP mapping
- Product containing zalcitabine (medicinal product) [SNOMED CT concept]
- Zalcitabine [ICD-11 Extension code]
- Zalcitabine [LOINC component]
- Zalcitabine (substance) [SNOMED CT concept]
- zalcitabine [MeSH Descriptor]
- zalcitabine [MeSH concept]
- zalcitabine [SNOMED Notion]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing zalcitabine (medicinal product) [SNOMED CT concept]
- Zalcitabine [ICD-11 Extension code]
- Zalcitabine [LOINC component]
- Zalcitabine (substance) [SNOMED CT concept]
- zalcitabine [ATC Code]
- zalcitabine [MeSH concept]
- zalcitabine [MeSH Descriptor]
- zalcitabine [SNOMED Notion]
Validated automatic mappings to BTNT
- zalcitabine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Bleomycin/Doxorubicin/Vincristine/zalcitabine [NCIt concept]
- Zalcitabine/Zidovudine [NCIt concept]

Keyword's position in hierarchy(ies) :

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