Receptor Down Regulation

Preferred Label : Receptor Down Regulation;

NCIt definition : A multicellular process that regulates the number of transmembrane receptors, by means of increased internalization or decreased expression of the transmembrane receptor. This process is involved in dampening the response to extracellular signals.;

Details

Origin ID

C42788;

UMLS CUI

C0949469;

Automatic exact mappings (from CISMeF team)
- down-regulation [MeSH Descriptor]
Currated CISMeF NLP mapping
- receptor Down-Regulation [MeSH concept]
Semantic type(s)
- Molecular Function [UMLS semantic type]
UMLS correspondences (same concept)
- receptor Down-Regulation [MeSH concept]
Validated automatic mappings to NTBT
- down-regulation [MeSH Descriptor]
biological_process_involves_gene_product
- Prostaglandin F2 Receptor Negative Regulator [NCIt concept]
process_involves_gene
- PTGFRN Gene [NCIt concept]
- PTGFRN wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients