Farnesylation Inhibition

Preferred Label : Farnesylation Inhibition;

NCIt definition : Farnesylation Inhibition involves interference with, or restraint of, enzymatic activities involved in covalent addition of farnesyl group(s) (three isoprene units) to polypeptide chains that contain the C terminal motif CAAX after assembly from messenger RNA at the ribosome.;

Details

Origin ID

C41581;

UMLS CUI

C1517133;

Semantic type(s)
- Molecular Function [UMLS semantic type]
biological_process_is_part_of_process
- Membrane Protein Traffic [NCIt concept]
- Post-Translational Regulation [NCIt concept]
is_physiologic_effect_of_chemical_or_drug
- BMS-214662 [NCIt concept]
- Perillyl Alcohol [NCIt concept]
- Tipifarnib [NCIt concept]

Keyword's position in hierarchy(ies) :

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