Polycythemia Vera, Polycythemic Phase

Preferred Label : Polycythemia Vera, Polycythemic Phase;

NCIt synonyms : Polycythemia Vera, Polycythemic Stage; Polycythemia Vera Polycythemic Stage;

NCIt definition : Polycythemia vera characterized by the proliferation of the erythroid, granulocytic, and megakaryocytic lineages. The peripheral blood shows excess of red blood cells, neutrophilia, and thrombocytosis. The bone marrow is hypercellular for the patient's age.;

Neoplastic status : Malignant;

Details

Origin ID

C41232;

UMLS CUI

C1514197;

Disease excludes abnormal cell
- Dacrocyte [NCIt concept]
- Hyperchromatic Megakaryocyte [NCIt concept]
- Segmented Neutrophil [NCIt concept]
Disease excludes normal cell origin
- Bone Marrow Stem Cell Committed to the Megakaryocytic Lineage [NCIt concept]
Disease may have findings
- Basophilia [NCIt concept]
- Chronic Clinical Course [NCIt concept]
- Dizziness [NCIt concept]
- Headache [NCIt concept]
- Hemorrhage [NCIt concept]
- Hepatomegaly [NCIt concept]
- Neutrophilia [NCIt concept]
- Paresthesia [NCIt concept]
- Pruritus [NCIt concept]
- Reticulin Fibrosis of the Bone Marrow [NCIt concept]
- Splenomegaly [NCIt concept]
- Thrombocytosis [NCIt concept]
Has associated anatomic sites
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_cytogenetic_abnormality
- Philadelphia Chromosome [NCIt concept]
- t(9;22)(q34.1;q11.2) [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Eosinophilia [NCIt concept]
- Ineffective Hematopoiesis [NCIt concept]
- Leukoerythroblastic Reaction [NCIt concept]
- Neutrophilia [NCIt concept]
- Not Otherwise Specified Lesion [NCIt concept]
- Osteosclerosis [NCIt concept]
- Poikilocytosis [NCIt concept]
disease_excludes_molecular_abnormality
- BCR-ABL1 Fusion Protein Expression [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Myeloid Cell [NCIt concept]
disease_has_finding
- Hypercellular Bone Marrow [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Bone Marrow Stem Cell [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Multipotent Bone Marrow Stem Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic Tissue [NCIt concept]
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_may_have_associated_disease
- Gout [NCIt concept]
- Myocardial Infarction [NCIt concept]
- Stroke [NCIt concept]
- Thrombophlebitis [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 8 [NCIt concept]
- Gain of Chromosome 9 [NCIt concept]
- Loss of Chromosome 13q [NCIt concept]
- Loss of Chromosome 1p [NCIt concept]
- Loss of Chromosome 20q [NCIt concept]
disease_may_have_molecular_abnormality
- JAK2 Exon 12 Mutation [NCIt concept]
- JAK2 NP_004963.1:p.V617F [NCIt concept]

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