Preferred Label : Nucleotide Excision Repair Inhibition;
NCIt definition : Nucleotide Excision Repair (NER) Inhibition involves interference with, or restraint
of, the activities that mend DNA regions containing chemical adducts, carcinogenic
adducts, or thymine dimers. During NER in eukaryotes, protein complexes detect DNA
shape irregularities, induce cuts on each side of the lesion, remove the damaged fragment,
and repair the helix by synthesis and ligation.;
Origin ID : C40662;
UMLS CUI : C1518460;
Semantic type(s)
- biological_process_is_part_of_process
- is_physiologic_effect_of_chemical_or_drug
