Early Placenta Insulin-Like Peptide

Preferred Label : Early Placenta Insulin-Like Peptide;

NCIt synonyms : EPIL; Insulin-Like Peptide-4; INSL4; Placentin; Insulin-Like Peptide 4;

NCIt definition : Early placenta insulin-like peptide (139 aa, 15 kDa) is encoded by the human INSL4 gene. This protein plays a role in both trophoblast development and bone formation.;

NCIt note : Similar to insulin, early placenta insulin-like peptide is cleaved at positions 26, 58 and 114 to release a two-chain 58 amino acid growth factor, which is comprised of an A chain and a B chain, and an 56 amino acid C peptide. (UniProt);

Details

Origin ID

C39673;

UMLS CUI

C0529145;

OMIM relation
- Insulin-like 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- INSL4 protein, human [MeSH concept]
- INSL4 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- INSL4 Gene [NCIt concept]
- Peptide Hormone Gene [NCIt concept]
gene_product_has_biochemical_function
- Peptide Hormone [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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