Preferred Label : Protein Export Pathway;
NCIt related terms : Protein Export;
Alternative definition : KEGG: Protein export is the active transport of proteins from the cytoplasm to the
exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria.
The sec dependent pathway is the general protein export system that transports newly
synthesized proteins into or across the cell membrane. The translocation channel is
formed from a conserved trimeric membrane protein complex, called the Sec61/SecY complex.
The twin-arginine translocation (Tat) pathway is another protein transport system
that transports folded proteins in bacteria, archaea, and chloroplasts. Many Tat systems
comprise three functionally different membrane proteins, TatA, TatB, and TatC, but
TatA and TatE seem to have overlapping functions, with TatA having by far the more
important role.;
KEGG ID : hsa03060;
Origin ID : C38857;
UMLS CUI : C1514545;
Semantic type(s)
- has_gene_product_element
- pathway_has_gene_element
