Preferred Label : Recombinant C5a;
NCIt synonyms : C5a; Therapeutic C5a;
NCIt definition : A recombinantly produced form of the complement C5a peptide, which is an endogenous
product generated by the cleavage of complement component C5 by C5 convertase. C5a
acts as an anaphylatoxin, which induces increased endothelial cell adhesion molecule
(CAM) expression, vascular permeability and smooth muscle cell contraction, and as
a chemokine, which promotes leukocyte migration and adhesion.;
CAS number : 80295-54-1;
NCI Metathesaurus CUI : CL448561;
Origin ID : C388;
UMLS CUI : C5574743;
Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
