HPV 16 E7:86-93 Peptide Vaccine

Preferred Label : HPV 16 E7:86-93 Peptide Vaccine;

NCIt synonyms : HPV-16E7 (86-93); E7(86-93) Lipopeptide; HPV 16E7 86-93 Lipopeptide Vaccine;

NCIt definition : A synthetic peptide vaccine consisting of amino acids 86 through 93 (TLGIVCPI) of the viral oncoprotein human papillomavirus (HPV) 16 E7. Vaccination with HPV-16 E7:86-93 peptide, which binds to HLA-A* 0201 molecule, may stimulate the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells positive for HPV-16 E7.;

Details

Origin ID

C38761;

UMLS CUI

C0879333;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Protein E7, Human Papillomavirus Type 16 [NCIt concept]
is_component_of_chemotherapy_regimen
- E7(86-93) Lipopeptide/HPV-16 E7(12-20) Peptide Vaccine/Montanide ISA-51 [NCIt concept]

Keyword's position in hierarchy(ies) :

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