Lamotrigine - CISMeF

Preferred Label : Lamotrigine;

NCIt definition : A synthetic phenyltriazine with antiepileptic and analgesic properties. Lamotrigine enhances the action of gamma-aminobutyric acid, an inhibitory neurotransmitter, which may result in a reduction of pain-related transmission of signals along nerve fibers. This agent may also inhibit voltage-gated sodium channels, suppress glutamate release, and inhibit serotonin reuptake. (NCI04);

Alternative definition : NCI-GLOSS: A drug that is used to help control some types of seizures. It is being studied in the prevention of peripheral neuropathy caused by some chemotherapy drugs. It belongs to the family of drugs called anticonvulsants.;

NCIt note : Clinical Trial--Chemotherapy-induced neuropathy;

UNII : U3H27498KS;

InChIKey : PYZRQGJRPPTADH-UHFFFAOYSA-N;

CAS number : 84057-84-1;

Drug name : Lamictal;

Chemical formula : C9H7Cl2N5;

ChEBI ID : CHEBI:6367;

Codes from synonyms : CDR0000335491;

Details

Origin ID

C38703;

UMLS CUI

C0064636;

Automatic exact mappings (from CISMeF team)
- lamoTRIgine:MCnc:Pt:Ser/Plas:Qn: [LOINC code]
- lamotrigine [EMDN type]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Lamotrigine [MeSH Descriptor]
- Lamotrigine (substance) [SNOMED CT concept]
- Product containing lamotrigine (medicinal product) [SNOMED CT concept]
- lamoTRIgine [LOINC component]
- lamotrigine [ATC Code]
- lamotrigine [Substance BNPC]
- lamotrigine [MeSH concept]
- lamotrigine [SNOMED Notion]
Validated automatic mappings to BTNT
- lamotrigine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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