NCIt definition : A recombinant therapeutic agent which is chemically identical to or similar to an
endogenous non-mutated melanocyte differentiation antigen expressed by both normal
and malignant melanocytes. Vaccinations with recombinant tyrosinase-related protein-2
may elicit an antitumoral cytotoxic T-cell response against tumor cells and some normal
cells that express tyrosinase-related protein-2. (NCI04);