Rilimogene Galvacirepvec

Preferred Label : Rilimogene Galvacirepvec;

NCIt synonyms : rVaccinia-Prostate-Specific Antigen/TRICOM Vaccine; Vaccinia-PSA-TRICOM Vaccine; Recombinant Vaccinia-PSA(L155)-TRICOM Vaccine; rVaccinia-PSA(L155)-TRICOM Vaccine; Recombinant Vaccinia-PSA(L155)/TRICOM Vaccine; Recombinant Vaccinia-PSA(L155)/TRICOM;

NCIt definition : A vaccine formulation consisting of recombinant vaccinia virus encoding prostate specific antigen (PSA) and recombinant vaccinia virus encoding three co-stimulatory molecule transgenes B7.1, ICAM-1, and LFA-3 (TRICOM). Vaccination with PSA in combination with TRICOM may enhance antigen presentation, resulting in the augmentation of a cytotoxic T cell (CTL) immune response against tumor cells expressing PSA.;

UNII : 59WJ3TGA5K;

CAS number : 1225283-43-1;

Drug name : PROSTVAC;

Molecule name : Prostvac-V;

NSC code : 717170;

Details

Origin ID

C38681;

UMLS CUI

C1515695;

Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Gene Regulation Process [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Prostate-Specific Antigen [NCIt concept]
is_component_of_chemotherapy_regimen
- Fowlpox-PSA-TRICOM Vaccine/Fowlpox-Sargramostim Vaccine/Vaccinia-Prostate-Specific Antigen-TRICOM Vaccine [NCIt concept]
- Fowlpox-PSA-TRICOM Vaccine/Sargramostim/Vaccinia-Prostate-Specific Antigen-TRICOM Vaccine [NCIt concept]
- Fowlpox-PSA-TRICOM Vaccine/Vaccinia-Prostate-Specific Antigen-TRICOM Vaccine [NCIt concept]

Keyword's position in hierarchy(ies) :

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