Clofibrate - CISMeF

Preferred Label : Clofibrate;

NCIt synonyms : Ethyl 2-(4-Chlorophenoxy)-2-methylpropanoate; Ethyl p-Chlorophenoxyisobyturate; 2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester; CFB;

NCIt related terms : Atromid S; Atromid-S;

NCIt definition : An aryloxyisobutyric acid derivate with antihyperlipidemic activity. Although the exact mechanism of action has not been fully characterized, clofibrate may enhance the conversion of very-low-density lipoprotein (VLDL) to low-density lipoprotein (LDL), decreasing the production of hepatic VLDL, inhibiting cholesterol production, and increasing fecal excretion of neutral sterols.;

UNII : HPN91K7FU3;

InChIKey : KNHUKKLJHYUCFP-UHFFFAOYSA-N;

CAS number : 637-07-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 637-07-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Atromid-S;

Chemical formula : C12H15ClO3;

NSC code : 79389;

ChEBI ID : CHEBI:3750;

Codes from synonyms : NSC0079389; 00377;

Details

Origin ID

C378;

UMLS CUI

C0009002;

Automatic exact mappings (from CISMeF team)
- Clofibrate [ICHI extension code]
- Complement factor b [OMIM gene]
- Complement factor b [OMIM Phenotype]
- Fibrate antihyperlipidemic (product) [Inactive SNOMED CT concept]
- Phylum Bacteroidetes (organism) [SNOMED CT concept]
- complement factor B [ORDO Gene]
Currated CISMeF NLP mapping
- Clofibrate [ICD-11 Extension code]
- Clofibrate [LOINC component]
- Clofibrate (substance) [SNOMED CT concept]
- clofibrate [Substance BNPC]
- clofibrate [MeSH Descriptor]
- clofibrate [MeSH concept]
- clofibrate [SNOMED Notion]
See also inter- (CISMeF)
- Product containing clofibrate (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Clofibrate [ICD-11 Extension code]
- Clofibrate [LOINC component]
- Clofibrate (substance) [SNOMED CT concept]
- Product containing clofibrate (medicinal product) [SNOMED CT concept]
- clofibrate [ATC Code]
- clofibrate [Substance BNPC]
- clofibrate [SNOMED Notion]
- clofibrate [MeSH Descriptor]
- clofibrate [MeSH concept]
Validated automatic mappings to BTNT
- clofibrate [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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