EWSR1-ATF1 Fusion Protein Expression

Preferred Label : EWSR1-ATF1 Fusion Protein Expression;

NCIt synonyms : EWS-ATF1 Fusion Protein Expression; EWS/ATF1 Fusion Protein Expression; EWSR1/ATF1 Fusion Protein Expression;

NCIt definition : A molecular abnormality characterized by the expression of a fusion protein that results from chromosomal recombination involving the human genes EWSR1 and ATF1. This abnormal protein is associated with hyalinizing clear cell carcinoma, malignant clear cell sarcoma of soft tissue and angiomatoid fibrous histiocytoma.;

Details

Origin ID

C37232;

UMLS CUI

C1512145;

Molecular abnormality of diseases
- Adult Clear Cell Sarcoma of Soft Tissue [NCIt concept]
- Advanced Clear Cell Sarcoma of Soft Tissue [NCIt concept]
- Angiomatoid Fibrous Histiocytoma [NCIt concept]
- Childhood Angiomatoid Fibrous Histiocytoma [NCIt concept]
- Childhood Clear Cell Sarcoma of Soft Tissue [NCIt concept]
- Clear Cell Sarcoma of Soft Tissue [NCIt concept]
- Dermal Clear Cell Sarcoma [NCIt concept]
- Gastrointestinal Clear Cell Sarcoma/Malignant Gastrointestinal Neuroectodermal Tumor [NCIt concept]
- Metastatic Clear Cell Sarcoma of Soft Tissue [NCIt concept]
- Recurrent Clear Cell Sarcoma of Soft Tissue [NCIt concept]
- Refractory Clear Cell Sarcoma of Soft Tissue [NCIt concept]
Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
molecular_abnormality_involves_gene
- ATF1 Gene [NCIt concept]
- EWSR1 Gene [NCIt concept]
- EWSR1/ATF1 Fusion Gene [NCIt concept]

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