Preferred Label : Cholesterol;
NCIt synonyms : (3beta)-Cholest-5-en-3-ol;
NCIt related terms : (-)-Cholesterol; 5-cholesten-3B-ol;
NCIt definition : An animal sterol found in the body tissues (and blood plasma) of vertebrates. It can
be found in large concentrations within the liver, spinal cord, and brain. Cholesterol
is an important component of the membranes of cells, providing stability. It is the
major precursor for the synthesis of vitamin D, of the various steroid hormones, including
cortisol, cortisone, and aldosterone in the adrenal glands, and of the sex hormones
progesterone, estrogen, and testosterone. Cholesterol also has an important role for
the brain synapses as well as in the immune system. In conditions featuring elevated
low density lipoproteins (LDL), cholesterol often forms plaque deposits in the walls
of arteries, a condition known as atherosclerosis, which is a major contributor to
coronary heart disease and other forms of cardiovascular disease.;
Alternative definition : NCI-GLOSS: A waxy, fat-like substance made in the liver, and found in the blood and
in all cells of the body. Cholesterol is important for good health and is needed for
making cell walls, tissues, hormones, vitamin D, and bile acid. Cholesterol also comes
from eating foods taken from animals such as egg yolks, meat, and whole-milk dairy
products. Too much cholesterol in the blood may build up in blood vessel walls, block
blood flow to tissues and organs, and increase the risk of developing heart disease
and stroke.; CRCH: Lipid composed of 27 carbon atoms which form three fused cycloheane (6-carbon)
rings, a cyclopentane (5-carbon ring) and a side chain of 8 carbon atoms. (Ensminger
et al).;
UNII : 97C5T2UQ7J;
InChIKey : HVYWMOMLDIMFJA-DPAQBDIFSA-N;
CAS number : 57-88-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 57-88-5
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Unit used : mg;
Chemical formula : C27H46O;
NSC code : 8798;
ChEBI ID : CHEBI:16113;
Codes from synonyms : CDR0000407756; NSC0008798; 00759;
Origin ID : C369;
UMLS CUI : C0008377;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
