Conventional Osteosarcoma

Preferred Label : Conventional Osteosarcoma;

NCIt synonyms : Intracortical Osteogenic Sarcoma; Conventional Central Osteosarcoma; COS; Intracortical Osteosarcoma;

NCIt related terms : Central osteosarcoma; Central; Medullary osteosarcoma;

NCIt definition : A high grade malignant bone-forming mesenchymal neoplasm producing osteoid. The tumor arises from the medullary portion of the bone. It affects the long bones and most commonly, the distal femur, proximal tibia, and proximal humerus. Pain with or without a palpable mass is the most common clinical presentation. It usually has an aggressive growth and may metastasize through the hematogenous route. The lung is the most frequent site of metastasis.;

Neoplastic status : Malignant;

ICD-O code : 9195/3; 9186/3;

Details

Origin ID

C35870;

UMLS CUI

C5848244;

Automatic exact mappings (from CISMeF team)
- Central osteosarcoma [ICD-O code]
- Central osteosarcoma [ICD-11 Extension code]
- Intracortical osteosarcoma [ICD-O code]
- Intracortical osteosarcoma [ICD-11 Extension code]
- collateral sulcus [UBERON concept]
- conventional central osteosarcoma [DO Concept]
- conventional osteosarcoma [DO Concept]
Currated CISMeF NLP mapping
- Central osteosarcoma (morphologic abnormality) [SNOMED CT concept]
- Intracortical osteosarcoma (morphologic abnormality) [SNOMED CT concept]
- central osteosarcoma [Radlex concept]
- intracortical osteosarcoma [Radlex concept]
DO Cross reference
- conventional osteosarcoma [DO Concept]
Disease excludes normal cell origin
- Bone Marrow Stem Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
Disease may have findings
- Lytic Bone Lesion [NCIt concept]
- Osteosclerotic Lesion [NCIt concept]
- Pain [NCIt concept]
- Pathologic Fracture [NCIt concept]
Excludes anatomical site(s)
- Soft Tissue [NCIt concept]
Has associated anatomic sites
- Bone [NCIt concept]
- Connective and Soft Tissue [NCIt concept]
- Musculoskeletal System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Anaplastic osteosarcoma [MedDRA LLT]
- Central osteosarcoma (morphologic abnormality) [SNOMED CT concept]
- Intracortical osteosarcoma (morphologic abnormality) [SNOMED CT concept]
- central osteosarcoma [Radlex concept]
- conventional osteosarcoma [DO Concept]
- intracortical osteosarcoma [Radlex concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
- OS Authorized Value Terminology [NCIt concept]
- OS Histology Table [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Intermediate Filaments Present [NCIt concept]
- Intracytoplasmic Eosinophilic Inclusion [NCIt concept]
disease_excludes_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Connective and Soft Tissue Cell [NCIt concept]
- Malignant Osteoblast [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Connective and Soft Tissue Cell [NCIt concept]
- Neoplastic Osteoblast [NCIt concept]
disease_has_finding
- Anaplastic Lesion [NCIt concept]
- Cellular Pleomorphism [NCIt concept]
- High Grade Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Osseous Differentiation [NCIt concept]
- Osteoid Formation [NCIt concept]
- Primary Lesion [NCIt concept]
- Vascular Channel Formation [NCIt concept]
disease_has_grade
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Connective and Soft Tissue Cell [NCIt concept]
- Osteoblast [NCIt concept]
disease_has_normal_tissue_origin
- Bone Tissue [NCIt concept]
- Connective Tissue [NCIt concept]
- Connective and Soft Tissue [NCIt concept]
- Medullary Bone [NCIt concept]
disease_has_primary_anatomic_site
- Bone [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Double Minutes [NCIt concept]
- Gain of Chromosome 1 [NCIt concept]
- Homogeneously Staining Region [NCIt concept]
- Loss of Chromosome 10 [NCIt concept]
- Loss of Chromosome 13 [NCIt concept]
- Loss of Chromosome 6q [NCIt concept]
- Loss of Chromosome 9 [NCIt concept]
- del(13q14) [NCIt concept]
disease_may_have_molecular_abnormality
- FOS Gene Amplification [NCIt concept]
- RB1 Gene Inactivation [NCIt concept]

Keyword's position in hierarchy(ies) :

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