NCIt definition : A bacterial infection of the colon secondary to infection with Clostridium difficile
bacteria. This infection generally results from the loss of normal gut flora secondary
to recent antibiotic use, and manifests as copious watery stools, with associated
abdominal pain and myalgia. C. difficile is the most common cause of pseudomembranous
colitis, and can progress to toxic megacolon if left untreated.;
Alternative definition : NICHD: An infection of the large intestine by the bacterium Clostridium difficile.;