Hypercalcemia of Malignancy

Preferred Label : Hypercalcemia of Malignancy;

NCIt definition : Hypercalcemia generally develops as a late complication of malignancy; its appearance has grave prognostic significance. It remains unclear, however, whether death is associated with hypercalcemic crisis (uncontrolled or recurrent progressive hypercalcemia) or with advanced disease. Symptoms include central nervous system impairment such as delirium with prominent symptoms of personality change, cognitive dysfunction, disorientation, incoherent speech, and psychotic symptoms such as hallucinations and delusions, smooth muscle hypotonicity, and altered cardiovascular function.;

Alternative definition : NICHD: Hypercalcemia due to a tumor production of parathyroid hormone-related protein or 1,25-dihydroxyvitamin D(3), or due to osteolytic metastases with local release of cytokines.;

Details

Origin ID

C3496;

UMLS CUI

C0149911;

Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Humoral hypercalcemia of malignancy (disorder) [SNOMED CT concept]
- Hypercalcaemia of malignancy [MedDRA Preferred Term]
- Hypercalcemia of malignancy [MedDRA LLT]
- Paraneoplastic hypercalcaemia [MedDRA LLT]
- Paraneoplastic hypercalcemia [MedDRA LLT]
- humoral hypercalcemia of malignancy [MeSH Supplementary Concept]
- humoral hypercalcemia of malignancy [MeSH concept]
- humoral hypercalcemia of malignancy [SNOMED Notion]
- hypercalcemia of malignancy [CISMeF Querying Strategy]
- hypercalcemia of malignancy [Disease (Nov.)]
associated_with_malfunction_of_gene_product
- Parathyroid Hormone-Related Protein [NCIt concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Endocrinology Terminology [NCIt concept]
is_finding_of_disease
- Childhood Ovarian Small Cell Carcinoma, Hypercalcemic Type [NCIt concept]
- Metastatic Ovarian Small Cell Carcinoma, Hypercalcemic Type [NCIt concept]
- Ovarian Small Cell Carcinoma, Hypercalcemic Type [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients