RBP2-Like Protein

Preferred Label : RBP2-Like Protein;

Obsolete resource : true;

NCIt synonyms : Jumonji Protein; RBBP2H1A; PUT1; Retinoblastoma-Binding Protein 2 Homolog 1A; JARID1B; PLU-1; PLU-1 Protein; AT Rich Interactive Domain 1B Protein;

NCIt definition : Widely expressed by human PLU-1 Gene (RBBP Family) at varying levels (highest in Sertoli cells), 1544-aa 176-kDa nuclear RBP2-Like Protein contains 3 Cys-rich zinc-binding DNA-binding PHD/LAP domains, a DNA-binding dead ringer domain, 5 putative nuclear localization signals, a putative DNA/chromatin binding motif, and other conserved regions of unknown function. With an additional 137 amino acids, 1681-aa 190-kDa RBBP2H1A appears to be an alternate PLU-1 product that shares 56% overall amino acid sequence identity with RBBP2, important in RB tumor suppressor regulation. (NCI);

NCIt note : See 'Putative DNA Chromatin Binding Motif 1';

Concept status : Retired_Concept;

Details

Origin ID

C34066;

UMLS CUI

C1321892;

OMIM relation
- Lysine demethylase 5b [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- KDM5B protein, human [MeSH Supplementary Concept]
- KDM5B protein, human [MeSH concept]

Keyword's position in hierarchy(ies) :

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