" /> Bleomycin - CISMeF





Preferred Label : Bleomycin;

NCIt synonyms : BLM;

NCIt related terms : Bleo;

NCIt definition : A mixture of glycopeptide antineoplastic antibiotics isolated from the bacterium Streptomyces verticillus. Bleomycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation.;

Alternative definition : NCI-GLOSS: The active ingredient in a drug that is used to treat many types of cancer and is being studied in the treatment of other types of cancer. It comes from the bacterium Streptomyces verticillus. Bleomycin damages DNA and may kill rapidly growing cancer cells. It is a type of antineoplastic antibiotic.;

UNII : 40S1VHN69B;

CAS number : 11056-06-7;

NSC code : 125066;

ChEBI ID : CHEBI:3139;

Codes from synonyms : NSC0125066; CDR0000045169; 73;

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28/05/2025


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