Phosducin - CISMeF

Preferred Label : Phosducin;

NCIt synonyms : G Beta Gamma Binding Protein; 33kDa Phototransducing Protein; MEKA Protein; PHD; Phosducin-Like Protein; Phosducin-Like Orphan Protein; PDC; Protein MEKA; 33 kDa Phototransducing Protein;

NCIt definition : Phosducin (246 aa, 28 kDa) is encoded by the human PDC gene. This protein plays a role in phototransduction and the inhibition of transcription factor activity in photoreceptor cells.;

NCIt note : Phosducin interacts with the beta and gamma subunits of the GTP-binding protein, transducin, and inhibits the activity of cone-rod homeobox protein (CRX). (UniProt);

Details

Origin ID

C30161;

UMLS CUI

C1739685;

Currated CISMeF NLP mapping
- phosducin [MeSH concept]
- phosducin [MeSH Supplementary Concept]
OMIM relation
- Phosducin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PDC protein, human [MeSH concept]
gene_encodes_gene_product
- PDC Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Visual Perception [NCIt concept]

Keyword's position in hierarchy(ies) :

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