NCIt synonyms : Alfa-N3 Interferon; Interferon Alfa-3N, Human Leukocyte Derived;
NCIt definition : A formulated therapeutic analog of the endogenous alpha interferon containing multiple
interferon species with antiviral and antitumor properties. Interferons bind to specific
cell-surface receptors, leading to the transcription and translation of genes with
an interferon-specific response element, thereby inducing: antiviral effects (the
most important being inhibition of viral protein synthesis); antiproliferative effects
(including inhibition of cellular growth and alteration of cellular differentiation);
anticancer effects (including interference with oncogene expression); and immune-modulating
effects (including activation of natural killer cells, alteration of cell surface
antigen expression, and augmentation of lymphocyte and macrophage cytotoxicity). (NCI04);
UNII : 47BPR3V3MP;
CAS number : 9008-11-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 9008-11-1
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