Small Nuclear Ribonucleoprotein F

Preferred Label : Small Nuclear Ribonucleoprotein F;

NCIt synonyms : Sma; SNRPF; SmF; Sm-F; Sm Protein F; snRNP-F; Small Nuclear Ribonucleoprotein Polypeptide-F; Small Nuclear Ribonucleoprotein Polypeptide F;

NCIt definition : Small nuclear ribonucleoprotein F (86 aa, 10 kDa) is encoded by the human SNRPF gene. This protein is involved in pre-mRNA splicing.;

NCIt note : Small nuclear ribonucleoprotein F (SNRPF) is a core component of the small nuclear ribonucleoprotein particles (snRNPs), U1, U2, U4/U6, and U5. The other snRNP core components are SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, and SNRPG. The core snRNP components are referred to as Sm proteins because they are targets for anti-Sm autoantibodies, which are diagnostic for systemic lupus erythematosus.;

Details

Origin ID

C30091;

UMLS CUI

C1700794;

Automatic exact mappings (from CISMeF team)
- Insulin-like growth factor-II [LOINC component]
- Proximal spinal muscular atrophy [ORDO Disease]
- Small nuclear ribonucleoprotein polypeptide f [OMIM gene]
- Somatomedin A (substance) [SNOMED CT concept]
- Spinal muscular atrophy, type I [OMIM Phenotype]
- Spinal muscular atrophy, type II [OMIM Phenotype]
- Spinal muscular atrophy, type III [OMIM Phenotype]
- Structure of superficial musculoaponeurotic system (body structure) [SNOMED CT concept]
- small nuclear Ribonucleoprotein-Associated protein F [MeSH concept]
- small nuclear ribonucleoprotein polypeptide F [HGNC gene]
- snRNP core proteins [MeSH Descriptor]
- spinal muscular atrophy [MedlinePlus Topic]
- survival of motor neuron 1, telomeric [ORDO Gene]
OMIM relation
- Small nuclear ribonucleoprotein polypeptide f [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- SNRPF protein, human [MeSH Supplementary Concept]
- SNRPF protein, human [MeSH concept]
- small nuclear Ribonucleoprotein-Associated protein F [MeSH concept]
gene_encodes_gene_product
- SNRPF Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Spliceosome Assembly Pathway [NCIt concept]
- Spliceosome Pathway [NCIt concept]
gene_product_is_physical_part_of
- Small Nuclear Ribonucleoprotein Particle [NCIt concept]
gene_product_plays_role_in_biological_process
- snRNP Biogenesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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