Phenylalanyl-tRNA Ligase Beta Subunit

Preferred Label : Phenylalanyl-tRNA Ligase Beta Subunit;

NCIt synonyms : Phenylalanyl-tRNA Synthetase Beta Chain; Phenylalanine-tRNA Ligase Beta Chain; PheRS; HSPC173; FRSB; FARSLB; Phenylalanyl-tRNA Synthetase Beta-Subunit; Phenylalanyl--tRNA Ligase Beta Subunit;

NCIt definition : Phenylalanine-tRNA ligase beta subunit (589 aa, 66 kDa) is encoded by the human FARSB gene. This protein plays a role in attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA.;

NCIt note : The cytoplasmic phenylalanine-tRNA synthetase enzyme is a heterotetrameric complex comprised of two phenylalanine-tRNA ligase beta subunit, which may act as regulatory subunits, and two phenylalanine--tRNA ligase alpha subunits, which may exert the catalytic activity of the enzyme.;

Details

Origin ID

C29589;

UMLS CUI

C1335400;

OMIM relation
- Phenylalanine-trna synthetase, beta subunit [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- FARSB Gene [NCIt concept]
- Translation Process Gene [NCIt concept]
gene_product_has_chemical_classification
- Protein Complex Subunit [NCIt concept]
gene_product_is_element_in_pathway
- Aminoacyl-tRNA Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Protein Synthesis [NCIt concept]
- Translation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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