Preferred Label : rMVA-PSA/PSMA/TRICOM;
NCIt synonyms : Modified Vaccinia Ankara Encoding PSA/PSMA/TRICOM; rMVA-PSA PSMA TRICOM;
NCIt definition : A cancer vaccine consisting of recombinant modified vaccinia Ankara (rMVA) encoding
the prostate specific antigen (PSA), the prostate-specific membrane antigen (PSMA)
and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM). Vaccination
with PSA/PSMA in combination with TRICOM may enhance antigen presentation, resulting
in the augmentation of a cytotoxic T cell (CTL) immune response against tumor cells
over-expressing PSA or PSMA.;
NSC code : 711154;
Origin ID : C29561;
UMLS CUI : C1515690;
Semantic type(s)
- has_target
