NCIt definition : A cancer vaccine consisting of a recombinant fowlpox virus encoding fragment of human
prostate-specific antigen (PSA), PSA:154-163 (155L), and a TRIad of COstimulatory
Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM). Administration of this agent may induce
a cytotoxic T cell response against PSA-expressing tumor cells. Dendritic cells infected
with TRICOM vectors greatly enhance naive T-cell activation and peptide-specific T-cell
stimulation. Fowlpox virus is an attractive vector because its genome is easy to manipulate
and it is replication incompetent in mammalian cells.;
UNII : 7PLH7RM47T;
CAS number : 1225283-42-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1225283-42-0
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