Preferred Label : Urea;
NCIt related terms : Ureaphil; carbamide;
NCIt definition : A nitrogenous compound containing a carbonyl group attached to two amine groups with
osmotic diuretic activity. In vivo, urea is formed in the liver via the urea cycle
from ammonia and is the final end product of protein metabolism. Administration of
urea elevates blood plasma osmolality, resulting in enhanced flow of water from tissues,
including the brain, cerebrospinal fluid and eye, into interstitial fluid and plasma,
thereby decreasing pressure in those tissues and increasing urine outflow.;
Alternative definition : NCI-GLOSS: A substance formed by the breakdown of protein in the liver. The kidneys
filter carbamide out of the blood and into the urine. Carbamide can also be made in
the laboratory. A topical form of carbamide is being studied in the treatment of hand-foot
syndrome (pain, swelling, numbness, tingling, or redness of the hands or feet that
may occur as a side effect of certain anticancer drugs).;
UNII : 8W8T17847W;
InChIKey : XSQUKJJJFZCRTK-UHFFFAOYSA-N;
CAS number : 57-13-6;
Drug name : Carbamide; Nutraplus; Elaqua XX; Aqua Care; Vanamide; Lanaphilic; Ureaphil;
Chemical formula : CH4N2O;
NSC code : 34375;
ChEBI ID : CHEBI:16199;
Codes from synonyms : CDR0000572226; CDR0000471785; 05047; NSC0034375;
Origin ID : C29531;
UMLS CUI : C0041942;
False automatic mappings
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
