Thioridazine Hydrochloride

Preferred Label : Thioridazine Hydrochloride;

NCIt definition : The hydrochloride salt form of thioridazine, a piperidine phenothiazine derivative and a dopamine antagonist with antipsychotic property. Thioridazine hydrochloride binds to mesolimbic postsynaptic dopamine receptor D2, thereby decreasing dopamine activity leading to decreased psychotic effects, such as hallucinations and delusions. In addition, this agent binds to serotonin 5-HT2 receptors, resulting in decreased serotonin activity.;

UNII : 4WCI67NK8M;

InChIKey : NZFNXWQNBYZDAQ-UHFFFAOYSA-N;

CAS number : 130-61-0;

Chemical formula : C21H26N2S2.HCl;

NSC code : 186060;

ChEBI ID : CHEBI:48566;

Details

Origin ID

C29498;

UMLS CUI

C0700499;

Currated CISMeF NLP mapping
- Thioridazine hydrochloride [Substance BNPC]
- Thioridazine hydrochloride (substance) [SNOMED CT concept]
- thioridazine hydrochloride [MeSH concept]
- thioridazine hydrochloride [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Thioridazine hydrochloride [Substance BNPC]
- Thioridazine hydrochloride (substance) [SNOMED CT concept]
- thioridazine hydrochloride [MeSH concept]
- thioridazine hydrochloride [SNOMED Notion]
Validated automatic mappings to NTBT
- thioridazine [Substance BNPC]
- thioridazine [MeSH Descriptor]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2D6 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Thioridazine [NCIt concept]
is_salt_form_of
- Thioridazine [NCIt concept]

Keyword's position in hierarchy(ies) :

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